All interface screens (like settings, inventory, character) crash/freeze Windows 10 so badly that hardware reset is needed to restart the PC.
This happens when you keep the interface screen open for more that 15 sec or so. The game works reasonably if you leave interface screens fast enough.
It is a current installation of the game (patch 1.04) downloaded and clean-installed and verified. Windows 10 Pro fully updated and verified.
All other top games run without problems on this rig.